Urticarial vasculitis - Cudurka Vaskulitis Ee 'Urticarial'
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ReferencesUrticarial vasculitis waa xaalad naadir ah oo lagu asteeyay xanuuno raagay ama soo noqnoqda. Astaamihiisa maqaarku waxay u ekaan karaan finan dabadheeraad ah, balse waa kuwo gaar ah sababtoo ah finan‑cuncunku waxay ku dheggan yihiin ugu yaraan 24 saacadood, waxayna keeni karaan dhibco madow ka dib marka ay libdhaan. Inkastoo inta badan sababta aan la garanayn, mararka qaarkood waxaa kicin kara daawooyinka qaarkood, caabuqyada, cudurrada difaaca jirka, cilladaha dhiigga, ama kansarrada. Daraasado qaar ayaa xitaa ku xirtay COVID‑19 iyo hargabka H1N1. Xanuunku sidoo kale wuu saameyn karaa qaybaha kale ee jidhka sida murqaha, kelyaha, sambabada, caloosha, iyo indhaha. Inkastoo baaritaanka unugga (biopsy) uu caawiyo xaqiijinta ogaanshaha, mar walba lagama maarmaan ma aha. Daaweynta caadi ahaan waxay ku bilaabataa antibiyootik, dapsone, colchicine, ama hydroxychloroquine xaaladaha fudud. Kiisaska aadka u daran, waxaa laga yaabaa in loo baahdo daawooyinka xakameeya habka difaaca jirka sida methotrexate ama corticosteroids. Dhawaan, daaweynta bayoolojiga (rituximab, omalizumab, interleukin‑1 inhibitors) waxay muujisay ballanqaad kiisaska adag.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Nin 35‑jir ah ayaa soo galay isagoo leh taariikh 15 maalmood ah oo casaan dhalaalaya ah, nabaro xanuun badan oo ka soo baxay labada cajar iyo lugaha, oo ay weheliyaan xanuun kala goysyo ah. Waxa uu ku dhacay caabuq kaadi‑mareenka ah muddo toddobaad ah ka hor inta aan finanku soo bixin. Maqaarkiisu waxa ka muuqday dhawr jeer oo jilicsan, giraan‑qaabeeya, qayb ahaan bannaan, iyo tabeello cas oo ku yaalla labada dhinac ee bowdyaha iyo lugaha. Waxa la siiyay prednisolone (40 mg/maalintii) afka laga qaato toddobaad, oo ay weheliso antihistamine‑ka aan hurdo lahayn (fexofenadine). Usbuuc gudihiis, dhammaan finanka ayaa si buuxda u baaba'ay. Ma jirin wax firiiric ah oo soo baxay 6‑da bilood ee soo socota ee baaritaanka caadiga ah.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Daawaynta – Daawooyinka OTC
Haddii aad qabto qandho (kulka jidhka oo kordha), waxaan kugula talineynaa inaad sida ugu dhakhsaha badan raadsato daryeel caafimaad.
Daawooyinka laga shakisan yahay inay keeni karaan dhibaato waa in la joojiyo (tusaale, antibiyootiga, dawooyinka caabuqa ee aan steroid ahayn).
Dawooyinka afka laga qaato sida cetirizine ama loratadine waxay ka caawiyaan xakameynta cuncunka.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Kareemka steroid-ka ee OTC wuxuu noqon karaa mid aan waxtar badan lahayn; waxaa laga yaabaa inuu u baahdo in la isticmaalo in ka badan toddobaad si horumar loo arko.
#Hydrocortisone ointment